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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBA1 All Species: 37.58
Human Site: S218 Identified Species: 82.67
UniProt: P22314 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22314 NP_003325.2 1058 117849 S218 S N G E Q P L S A M V S M V T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092142 1058 117902 S218 S N G E Q P L S A M V S M V T
Dog Lupus familis XP_538014 1015 112483 S218 S N G E Q P L S A M V S M V T
Cat Felis silvestris
Mouse Mus musculus Q02053 1058 117790 S218 S N G E Q P L S A M V S M V T
Rat Rattus norvegicus Q5U300 1058 117769 S218 S N G E Q P L S A M V S M V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080185 1059 117949 S217 P N G E Q P L S A M I S M I T
Zebra Danio Brachydanio rerio NP_998227 1058 118200 S218 T N G E Q P L S A M I S M I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477310 1191 130740 S363 Q D G T Q P I S T M I A S I T
Honey Bee Apis mellifera XP_394434 1049 117087 S217 I N G E P P V S A M V A S I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795302 1054 117556 S215 S T G E E P M S V M V S A V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22515 1024 114248 N223 V E G L D K L N D G T L F K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 90.2 N.A. 95.5 96.4 N.A. N.A. N.A. 77.6 78.8 N.A. 54.1 62.2 N.A. 65.2
Protein Similarity: 100 N.A. 99 92.1 N.A. 97.5 98.1 N.A. N.A. N.A. 90.1 90 N.A. 67.3 76.9 N.A. 80.7
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 80 80 N.A. 40 53.3 N.A. 60
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 100 N.A. 73.3 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 73 0 0 19 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 10 0 82 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 100 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 28 0 0 37 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 10 0 0 73 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 91 0 0 64 0 0 % M
% Asn: 0 73 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 10 91 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 55 0 0 0 0 0 0 91 0 0 0 73 19 0 19 % S
% Thr: 10 10 0 10 0 0 0 0 10 0 10 0 0 0 73 % T
% Val: 10 0 0 0 0 0 10 0 10 0 64 0 0 55 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _